Best Things to Do from Miami to Key West: Road Trip Guide


An unforgettable journey awaits as we explore the route from Miami to Key West, a road trip renowned for its coastal beauty, cultural diversity, and gastronomic delights. This guide will uncover hidden gems, must-see landmarks, and reveal tantalizing tastes that define the very soul of this part of sunny Florida.

Delving into Miami’s Allure

As we kick-start this journey, we find ourselves in the heart of vibrant Miami. A city that beats to the rhythm of its Latin roots and revels in its contemporary, cosmopolitan vibe.

It’s a magical melange of sun-kissed beaches, towering palm trees, art deco architecture, and a nightlife that dances until dawn. No wonder they call it ‘The Magic City’.

The allure of Miami goes beyond its beautiful beaches. Its soul is as vibrant as its neon lights, with a thriving art scene, diverse neighborhoods, and rich cultural history.

From the graffiti murals in Wynwood Walls, the chic vibes of Miami Design District, to the Cuban flair in Little Havana, Miami is a city that celebrates its diversity with unadulterated enthusiasm.

Vizcaya Museum Gardens Miami Beautiful
Miami Little Havana Building

Before we embark on our route to Key West, we recommend soaking in some of Miami’s must-see sights. Start with a stroll down the iconic Ocean Drive, where the heart of Miami beats.

Don’t miss the Vizcaya Museum and Gardens, an opulent reminder of Miami’s golden age. For a breath of fresh air, head to the tropical paradise that is Fairchild Tropical Botanic Garden, a haven for rare, exotic plants.

Finally, if you have time, lose yourself in the Pérez Art Museum Miami, a modern and contemporary art museum designed to include the city’s diverse community.

Planning Your Route

Hitting the road from Miami to Key West is about more than the destination—it’s a journey. A journey filled with breathtaking vistas, quirky roadside attractions, and a peek into the soul of Florida.

The most scenic and popular route to Key West is along the legendary Overseas Highway (U.S. Route 1), an engineering marvel that stretches 113 miles and includes 42 bridges, making it seem like you’re flying over the turquoise sea.

This route, often referred to as the “Highway that Goes to Sea,” will guide you through vibrant towns, natural parks, and stunning keys, each with its unique charm.

Miami To Key West Long Bridges

Although Florida is blessed with warm weather all year round, the best time to make this trip is during the dry season, from November to April. The weather during these months is perfect for outdoor activities and exploring the keys.

Keep in mind that this route can get quite busy during holidays and spring break, so if you prefer a less crowded journey, consider planning your trip during off-peak times.

Unleashing Your Inner Foodie

Embarking on this journey means not only feasting your eyes on the incredible views but also tantalizing your taste buds with the region’s delicious cuisine. This route is a gastronomic delight, offering some of the best seafood and Cuban influenced dishes in the U.S.

As you travel from Miami to Key West, make sure you indulge in some of the iconic dishes of the region. This includes stone crabs, a local delicacy in the Florida Keys, and the traditional Cuban sandwich, a flavorful tribute to the Cuban influence in Miami. Don’t forget to try the Key Lime Pie, a tangy dessert that Key West is famously known for!

Miami Key West Cuban Sandwich
Traditional Cuban sandwich

Whether you’re looking for a roadside shack serving the freshest catch of the day or a fancy restaurant with ocean views, there are numerous eateries to satisfy your culinary cravings.

Some highly recommended spots include the Garcia’s Seafood Grille in Miami, famed for their fresh-off-the-boat fish, and Blue Heaven in Key West, where you can enjoy your Key Lime Pie under a canopy of tropical trees.

Discovering Natural Wonders

The journey from Miami to Key West isn’t just a road trip; it’s a voyage through some of the most enchanting natural wonders Florida has to offer.

This trip presents countless opportunities to witness the region’s diverse flora and fauna, vibrant ecosystems, and pristine beaches.

A detour to Everglades National Park is a must for any nature enthusiast. This UNESCO World Heritage site, often referred to as the ‘River of Grass’, is a vibrant ecosystem teeming with a variety of wildlife.

Everglades National Park Angry Crocodile
Matthew Paulson
Bahia Honda State Park Review
Ben Hagen

From alligators basking on the riverbanks, flamingos wading in the shallows, to the elusive Florida panther, it’s a wildlife lover’s dream come true.

En route to Key West, you’ll find Bahia Honda State Park, home to some of the most pristine beaches in Florida. Its azure waters and white sandy beaches make it a haven for sun-seekers. Besides lounging on the beach, the park offers fantastic opportunities for snorkeling, kayaking, and camping.

Immersing in Local Culture

Experience the heart and soul of the region by diving into its rich cultural tapestry. Every stop along this route brings you closer to the history, traditions, and lifestyle of the locals.

Start your cultural immersion in Miami’s Little Havana, a vibrant neighborhood brimming with Cuban culture. The streets here are alive with the sounds of salsa, the smell of fresh Cuban coffee, and the sight of old men passionately engaged in games of Dominoes.

Visit the Cuban Memorial Boulevard, and don’t forget to try a classic Mojito at Ball & Chain.

Gerard Hilinski
Key West Sunset Mallory Square

Once you reach Key West, step back in time at the historic Ernest Hemingway Home and Museum, where the famous writer lived and worked.

Visit the Key West Lighthouse, which offers panoramic views of the island. To truly immerse yourself in the Key West spirit, end your day at Mallory Square’s Sunset Celebration, a nightly arts festival that encapsulates the laid-back, artistic vibe of the island.

Thrills and Adventures

The azure waters of the Florida Keys are a paradise for water sports enthusiasts. From jet-skiing in Miami, paddleboarding in Islamorada, to deep-sea fishing in Marathon, there’s no shortage of aquatic adventures.

The clear, warm waters of the Florida Keys are home to the only living coral barrier reef in the continental U.S., making it a hotspot for diving and snorkeling.

Notable dive spots include John Pennekamp Coral Reef State Park and the famous Christ of the Abyss underwater statue. Whether you’re a seasoned diver or a first-timer, exploring the underwater wonders of the Keys is an unforgettable experience.

Night to Remember

As the sun sets, the Miami to Key West route lights up with an eclectic mix of nightlife options that’ll make your nights as memorable as your days.

Miami is famous for its vibrant nightlife. From salsa dancing at Ball & Chain in Little Havana, sipping craft cocktails at a rooftop bar in Brickell, to partying until dawn in one of South Beach’s world-renowned clubs, Miami offers an array of options to suit all nocturnal tastes.

Key West Local Events Mallory Square

In contrast to Miami’s high-energy nightlife, Key West offers a more laid-back evening scene.

Catch the Sunset Celebration at Mallory Square, a nightly festival featuring street performers, local artisans, and food carts. Continue your night with a visit to Sloppy Joe’s, a favorite bar of Ernest Hemingway, or enjoy some live music at the iconic Green Parrot Bar.

Don’t forget to look up; the lack of light pollution in Key West means you’ll have an incredible view of the starlit sky.

Concluding the Journey

After journeying through so many beautiful landscapes and vibrant communities, you’ll end your trip in the magical town of Key West.

Spend your day wandering through the colorful historic district, cooling off in the crystal-clear waters, or simply unwinding at a beachside cafe. However you choose to spend your day, you’re sure to fall in love with Key West’s unique charm.

As we bid farewell to the Keys, we’re not just leaving behind sun-soaked beaches and turquoise waters. We’re also parting with the vibrant flavors of the local cuisine, the echoes of salsa music, and the warm hospitality of the locals.

But the journey doesn’t have to end here – you can always come back or continue your exploration of the Sunshine State!


From the vibrant streets of Miami to the relaxed island vibe of Key West, this road trip offers an unparalleled blend of adventure, culture, gastronomy, and natural beauty.

Whether it’s a day trip or a leisurely week-long journey, this route is sure to leave you with unforgettable memories and a longing to return.